Aspirin - Revision history

Michel Lamontagne: /* Main production path */

2021-05-26T15:25:36Z

Main production path

Michel Lamontagne: /* Alternate biological production */

2021-05-26T15:12:42Z

Alternate biological production

Michel Lamontagne: /* Main production path */

2021-05-26T15:10:49Z

Main production path

Michel Lamontagne at 15:01, 26 May 2021

2021-05-26T15:01:18Z

Michel Lamontagne at 15:00, 26 May 2021

2021-05-26T15:00:55Z

Michel Lamontagne at 15:00, 26 May 2021

2021-05-26T15:00:43Z

Michel Lamontagne: developed a path for production

2021-05-26T15:00:13Z

developed a path for production

Michel Lamontagne at 14:56, 26 May 2021

2021-05-26T14:56:55Z

Michel Lamontagne: /* In situ production */

2021-05-26T14:50:48Z

In situ production

Michel Lamontagne at 14:17, 26 May 2021

2021-05-26T14:17:54Z

@@ Line 10: / Line 10: @@
 ====Main production path====
-[[Methane]] (CH4) + Catalytic reforming -> mixture of aromatic hydrocarbons including Toluene and Benzene
+[[Methane]] (CH4) + Catalytic reforming (or via methanol production<ref>https://aiche.onlinelibrary.wiley.com/doi/abs/10.1002/aic.15144</ref>) -> mixture of aromatic hydrocarbons including Toluene and Benzene
 Separation by [[distillation]] -> Toluene (C<sub>7</sub>H<sub>8</sub>)

@@ Line 35: / Line 35: @@
 ===Alternate biological production===
-It may be more practical to produce aspirin from the bark of the willow tree, that contains the amino acid Phenylalanine. however, this requires the mastery of enzyme catalyzed processes.
+It may be more practical to produce aspirin from the bark of the willow tree, that contains the amino acid Phenylalanine. However, this requires the mastery of enzyme catalyzed processes.
 ==References==
 Wikipedia article [[w:Salicylic_acid|Salicylic acid]]

@@ Line 1: / Line 1: @@
 [[File:Aspirin-skeletal.png|thumb|200x200px|Aspirin molecule]]
 Aspirin is the brand name for Salicylic acid.  Its production on Mars would be part of a larger chemical production system, and it can be used as a model for the complexity of the chemical industry that would be required for a Mars Settlement.  The chemical formula of Salicylic acid is C<sub>7</sub>H<sub>6</sub>O<sub>3</sub>.
 __NOTOC__
 ==[[In-situ resource utilization|In situ production]]==
@@ Line 6: / Line 7: @@
 Aspirin could be synthesized from simple precursor molecules using the following synthesis path:
-=== Chemical synthesis of Salicylic acid ===
+===Chemical synthesis of Salicylic acid===
 ====Main production path====
-Methane (CH4) + Catalytic reforming -> mixture of aromatic hydrocarbons including Toluene and Benzene
+[[Methane]] (CH4) + Catalytic reforming -> mixture of aromatic hydrocarbons including Toluene and Benzene
-Separation by distillation -> Toluene (C<sub>7</sub>H<sub>8</sub>)
+Separation by [[distillation]] -> Toluene (C<sub>7</sub>H<sub>8</sub>)
-Toluene + O<sub>2</sub> in a cobalt catalyzed reaction -> Benzoic acid (C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)
+Toluene + [[Oxygen|O<sub>2</sub>]] in a cobalt catalyzed reaction -> Benzoic acid (C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)
 Benzoic acid + molten Sodium benzoate(C<sub>6</sub>H<sub>5</sub>COONa) in a copper-catalyzed reaction -> Phenol (C<sub>6</sub>H<sub>5</sub>OH)
@@ Line 33: / Line 34: @@
 Sodium hydroxide (NaOH) is produced by the electrolysis of sodium chloride(NaCl-table salt) using the Chloralkali process.
-=== Alternate biological production ===
+===Alternate biological production===
 It may be more practical to produce aspirin from the bark of the willow tree, that contains the amino acid Phenylalanine. however, this requires the mastery of enzyme catalyzed processes.
 ==References==
 Wikipedia article [[w:Salicylic_acid|Salicylic acid]]

@@ Line 1: / Line 1: @@
 [[File:Aspirin-skeletal.png|thumb|200x200px|Aspirin molecule]]
 Aspirin is the brand name for Salicylic acid.  Its production on Mars would be part of a larger chemical production system, and it can be used as a model for the complexity of the chemical industry that would be required for a Mars Settlement.  The chemical formula of Salicylic acid is C<sub>7</sub>H<sub>6</sub>O<sub>3</sub>.
-__NO TOC__
+__NOTOC__
 ==[[In-situ resource utilization|In situ production]]==

@@ Line 1: / Line 1: @@
 [[File:Aspirin-skeletal.png|thumb|200x200px|Aspirin molecule]]
 Aspirin is the brand name for Salicylic acid.  Its production on Mars would be part of a larger chemical production system, and it can be used as a model for the complexity of the chemical industry that would be required for a Mars Settlement.  The chemical formula of Salicylic acid is C<sub>7</sub>H<sub>6</sub>O<sub>3</sub>.
-__No TOC__
+__NO TOC__
 ==[[In-situ resource utilization|In situ production]]==

@@ Line 1: / Line 1: @@
 [[File:Aspirin-skeletal.png|thumb|200x200px|Aspirin molecule]]
-Aspirin is the brand name for Salicylic acid.  It's production on Mars would be part of a larger chemical production system, and it can be used as a model for the complexity of the chemical industry that would be required for a Mars Settlement.
+Aspirin is the brand name for Salicylic acid.  Its production on Mars would be part of a larger chemical production system, and it can be used as a model for the complexity of the chemical industry that would be required for a Mars Settlement.  The chemical formula of Salicylic acid is C<sub>7</sub>H<sub>6</sub>O<sub>3</sub>.
 ==In situ production==
-Aspirin can be synthesized from simple precursor molecules using the following synthesis path:
+Aspirin could be synthesized from simple precursor molecules using the following synthesis path:
-==== Main Salicylic acid production path ====
+====Main Salicylic acid production path====
 Methane (CH4) + Catalytic reforming -> mixture of aromatic hydrocarbons including Toluene and Benzene
 Separation by distillation -> Toluene (C<sub>7</sub>H<sub>8</sub>)
-Toluene + O<sub>2</sub> in a cobalt catalyzed reaction -> benzoic acid (C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)
+Toluene + O<sub>2</sub> in a cobalt catalyzed reaction -> Benzoic acid (C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)
-Benzoic acid + molten sodium benzoate(C<sub>6</sub>H<sub>5</sub>COONa) in a copper-catalyzed reaction -> Phenol (C<sub>6</sub>H<sub>5</sub>OH)
+Benzoic acid + molten Sodium benzoate(C<sub>6</sub>H<sub>5</sub>COONa) in a copper-catalyzed reaction -> Phenol (C<sub>6</sub>H<sub>5</sub>OH)
-Phenol + sodium hydroxide(NaOH) ->  sodium phenoxide (NaOC<sub>6</sub>H<sub>5</sub>)
+Phenol + Sodium hydroxide(NaOH) ->  Sodium phenoxide (NaOC<sub>6</sub>H<sub>5</sub>)
 Sodium phenoxide +CO<sub>2</sub> at 100 atm and 115 °C  in a method known as the Kolbe-Schmitt reaction -> sodium salicylate (C<sub>7</sub>H<sub>5</sub>NaO<sub>3)</sub>
@@ Line 21: / Line 21: @@
 Sodium salicylate + acidification with [[Sulfuric acid|sulfuric acid]] ->
 Salicylic acid
-==== Sodium benzoate production ====
+====Sodium benzoate production====
-Benzoic acid(C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)  + Sodium hydroxyde (NaOH) -> sodium benzoate (C<sub>6</sub>H<sub>5</sub>COONa)
+Benzoic acid(C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)  + Sodium hydroxide (NaOH) -> sodium benzoate (C<sub>6</sub>H<sub>5</sub>COONa)
-==== Sodium hydroxide production ====
+====Sodium hydroxide production====
 Sodium hydroxide is also known as caustic soda.
@@ Line 32: / Line 32: @@
 It may be more practical to produce aspirin from the bark of the willow tree, that contains the amino acid Phenylalanine. however, this requires the mastery of enzyme catalyzed processes.