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Aspirin can be synthesized from simple precursor molecules using the following synthesis path:  
Aspirin can be synthesized from simple precursor molecules using the following synthesis path:  


==== Main Salicylic acid production path ====
Methane (CH4) + Catalytic reforming -> mixture of aromatic hydrocarbons including Toluene and Benzene  
Methane (CH4) + Catalytic reforming -> mixture of aromatic hydrocarbons including Toluene and Benzene  


Separation by distillation -> Toluene (C<sub>7</sub>H<sub>8</sub>)  
Separation by distillation -> Toluene (C<sub>7</sub>H<sub>8</sub>)  


Toluene + O<sub>2</sub> in a copper-catalyzed reaction of molten sodium benzoate-> Phenol (C<sub>6</sub>H<sub>5</sub>OH)  
Toluene + O<sub>2</sub> in a cobalt catalyzed reaction -> benzoic acid (C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)  


Phenol + sodium hydroxide ->  sodium phenoxide (NaOC<sub>6</sub>H<sub>5</sub>)
Benzoic acid + molten sodium benzoate(C<sub>6</sub>H<sub>5</sub>COONa) in a copper-catalyzed reaction -> Phenol (C<sub>6</sub>H<sub>5</sub>OH)
 
Phenol + sodium hydroxide(NaOH) ->  sodium phenoxide (NaOC<sub>6</sub>H<sub>5</sub>)


Sodium phenoxide +CO<sub>2</sub> at 100 atm and 115 °C  in a method known as the Kolbe-Schmitt reaction -> sodium salicylate (C<sub>7</sub>H<sub>5</sub>NaO<sub>3)</sub>
Sodium phenoxide +CO<sub>2</sub> at 100 atm and 115 °C  in a method known as the Kolbe-Schmitt reaction -> sodium salicylate (C<sub>7</sub>H<sub>5</sub>NaO<sub>3)</sub>
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Salicylic acid
Salicylic acid


Sodium benzoate
==== Sodium benzoate production ====
Benzoic acid(C<sub>7</sub>H<sub>6</sub>O<sub>2</sub>)  + Sodium hydroxyde (NaOH) -> sodium benzoate (C<sub>6</sub>H<sub>5</sub>COONa)
 
==== Sodium hydroxide production ====
Sodium hydroxide is also known as caustic soda.


sodium hydroxyde
Sodium hydroxide (NaOH) is produced by the electrolysis of sodium chloride using the Chloralkali process.


It may be more practical to produce aspirin from the bark of the willow tree, that contains the amino acid Phenylalanine. however, this requires the mastery of enzyme catalyzed processes.
It may be more practical to produce aspirin from the bark of the willow tree, that contains the amino acid Phenylalanine. however, this requires the mastery of enzyme catalyzed processes.

Revision as of 15:50, 26 May 2021

Aspirin molecule

Aspirin is the brand name for Salicylic acid. It's production on Mars would be part of a larger chemical production system, and it can be used as a model for the complexity of the chemical industry that would be required for a Mars Settlement.

In situ production

Aspirin can be synthesized from simple precursor molecules using the following synthesis path:

Main Salicylic acid production path

Methane (CH4) + Catalytic reforming -> mixture of aromatic hydrocarbons including Toluene and Benzene

Separation by distillation -> Toluene (C7H8)

Toluene + O2 in a cobalt catalyzed reaction -> benzoic acid (C7H6O2)

Benzoic acid + molten sodium benzoate(C6H5COONa) in a copper-catalyzed reaction -> Phenol (C6H5OH)

Phenol + sodium hydroxide(NaOH) -> sodium phenoxide (NaOC6H5)

Sodium phenoxide +CO2 at 100 atm and 115 °C in a method known as the Kolbe-Schmitt reaction -> sodium salicylate (C7H5NaO3)

Sodium salicylate + acidification with sulfuric acid ->

Salicylic acid

Sodium benzoate production

Benzoic acid(C7H6O2) + Sodium hydroxyde (NaOH) -> sodium benzoate (C6H5COONa)

Sodium hydroxide production

Sodium hydroxide is also known as caustic soda.

Sodium hydroxide (NaOH) is produced by the electrolysis of sodium chloride using the Chloralkali process.

It may be more practical to produce aspirin from the bark of the willow tree, that contains the amino acid Phenylalanine. however, this requires the mastery of enzyme catalyzed processes.